Purnima Justa

By Nancy Jaswal, Purnima Justa, Hemant Kumar, Deepshikha, Krishna, Balaram Pani and Pramod Kumar

Nowadays, nanoparticles are used in a variety of biological applications where they enhance treatments and laboratory tests. Due to their distinctive properties and minor adverse effects, nanoparticles are being used more specifically for medication delivery, not only in the treatment of cancer but also for other diseases. Magnetic nanoparticles like SPION (superparamagnetic Iron Oxide nanoparticles) are regarded to be the most viable in the midst of these materials. SPION are frequently used in biomedical applications due to their low cost and lack of toxicity. Within the developing field of nanomedicine, superparamagnetic iron oxide nanoparticles (SPION) are basic technological classes that have been widely studied for cancer imaging and treatment. Additionally, SPION employ super paramagnets, which seem to be beneficial for focusing on particular tumor areas within a body. For instance, the superparamagnetic abilities of magnetite (Fe₃O₄), which are frequently utilized in delivery of drug, diagnosis and therapy. SPION was envisioned as a tool for the “golden therapeutic era” since it minimized cellular absorption by macrophages, targeted cancer cells preferentially while sparing healthy cells, monitored cancer cells before and after therapy, and controlled drug release. In order to give a concise overview of SPION, there will be focus on their biomedical applications includes hyperthermia (HT), magnetic resonance imaging (MRI), magnetic drug targeting (MDT), gene delivery as well as nanomedicine.

Part of the book: Iron Ores and Iron Oxides