Giovanni Palleschi

NEFROCENTER, Medica San Carlo, Frascati

Giovanni Palleschi (MD, Ph.D.) graduated in 1997 and specialized in urology in 2002 at Sapienza University of Rome. In 2002 he won a prize for research on anatomo-clinical correlations of urinary disorders in patients with multiple sclerosis, and in 2011 he achieved a physician doctorate in human anatomy, dermatology, and plastic surgery. He has been a member of the Scientific Committees of the Italian Society of Urology, the Italian Society of Urodynamics, and the European Association of Urology. He participated as a co-investigator in numerous clinical trials. He is the author of 70 publications edited on PubMed and scientific books. He participated in academic teaching activities at the Sapienza University of Rome. At present, he is a consultant urologist for the Nefrocenter Group (Italy).

1books edited

3chapters authored

Latest work with IntechOpen by Giovanni Palleschi

In clinical practice, all physicians have to deal with patients suffering from chronic kidney disease. Large numbers of these patients suffer from mild conditions, but nevertheless, they deserve special attention because inappropriate management may accelerate kidney function deterioration. On the other side, patients affected by end-stage renal disease require replacement therapies and often represent a challenge for clinicians due to their complex pathophysiology. Therefore, an adequate knowledge of the most important clinical and therapeutic aspects of renal failure is an essential requirement for every doctor, especially if we consider the increasing incidence and prevalence of this condition. The book summarises the most important etiopathogenetic and pathophysiologic aspects of chronic kidney disease and focuses the attention on important emerging topics: nutritional and dietary management, renoprotective interventions, new evidence about pathophysiological mechanisms provided by base research, innovations in pharmacological treatment, and strategies to improve patient’s quality of life. Data are reported in clear and concise language, supported by graphics, tables, and pictures that facilitate the comprehension of all the arguments.

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Chronic Kidney Disease

Edited by Giovanni Palleschi

Books edited

Cystitis

Edited by Giovanni Palleschi

Chapters authored

Quality of Life in Neurogenic Bladder Patients and Improvement after Botulinum Toxin Injection

By Giovanni Palleschi and Antonio Cardi

Various neurogenic conditions may determine an altered function of the bladder and urethral sphincters leading to urinary symptoms. Among these symptoms, loss of urine is considered the most bothersome, and recent literature has proposed that urinary incontinence and poor quality of life should be considered as associated conditions. Urinary incontinence is responsible for reducing the enjoyment of life, including loss of self-confidence and limitation of social activity; it is also associated with anxiety, depression, and deterioration in sexual life, and reduced physical activity. Conservative treatments represent a first-line therapeutic approach to neurogenic urinary disorders, followed by oral medications. However, these treatments often do not provide complete recovery from symptoms, especially from urinary incontinence. Onabotulimun toxin A has proven to be safe and effective for treating neurogenic urinary incontinence and its use is associated with a strong improvement of patients’ quality of life. Furthermore, this treatment lowers the risk of severe complications to the upper urinary tract, reducing the need for hospitalization. Quality of life improvement as well as clinical efficacy must be considered targets of the therapy, and the use of onabotulimun toxin A for treating neurogenic urinary incontinence reaches both these goals.

Part of the book: Botulinum Toxin

Introductory Chapter: Presenting an Overview on the Main Clinical, Diagnostic and Therapeutic Aspects of Human Cystitis

By Giovanni Palleschi

Part of the book: Cystitis

Introductory Chapter: Chronic Kidney Disease – Introductive Overview and Current Issues

By Giovanni Palleschi

Chronic Kidney Disease is reported as a “Kidney damage for ≥3 months, as defined by structural or functional abnormalities of the kidney, with or without decreased GFR or GFR”. Chronic Kidney Disease is a progressive condition and it has a significant negative impact on general population morbidity of and quality of life (Qol). The increase of Chronic Kidney Disease prevalence throughout the world is becoming a challenge for two main reasons: first of all, it will require in the next future an improvement of resources available to face the number of patients who’ll need medical assistance; secondarily, it will cause an increase of the costs for publich healthcare systems. Patients suffering from Chronic Kidney Disease have generically an increase risk to death and complications associated with this condition which causes over 1 million of deaths per year in the world. Basing on epidemiological data provided by the most important studies, Chronic Kidney Disease is expected to become one of the most prevalent conditions in industrial and rural countries and one of the most important causes of death. Strategies for prevention, improvement of therapeutic options to delay disease progression, and new perspectives that could replace the invasive methods today available to treat end stage renal disease are warranted to improve patients’ quality of life, wellness of population and to provide a favourable impact on public healthcare systems.

Part of the book: Chronic Kidney Disease

Giovanni Palleschi

Latest work with IntechOpen by Giovanni Palleschi

Chronic Kidney Disease

Books edited

Cystitis

Chapters authored

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Tamara Kosyreva

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