Chapters authored
Growth Hormone and Kynesitherapy for Brain Injury Recovery
Part of the book: Brain Injury
Pituitary Growth Hormone Secretion and Cell Growth Hormone Production: Regulation of Their Secretion and Their Signaling Pathways
Growth hormone (GH) performs very diverse functions in the organism, and this is the reason by which the regulation of the secretion of this hormone is very complex; although the primary regulators are growth hormone-releasing hormone (GHRH) and somatostatin, it is in turn regulated mainly by adrenergic and cholinergic pathways, and other factors can act directly on its secretion, particularly on the somatostatin, thus affecting the pituitary secretion of GH. In this chapter, we will analyze the transcription of GH gene and how GH release is affected by different neurotransmitters, metabolic substrates, feeding and fasting, and other hormones, placing special emphasis on why pituitary secretion of GH is sexually dimorphic.
Part of the book: Growth Hormone
Growth Hormone Gene Family and Its Evolution
In this review, we will analyze the family of growth hormone (GH) genes, the territories where they are produced, the proteolytic generation of GH isoforms, both at the pituitary and tissue levels, the biological activity of these molecular forms, and we will describe the new variant GH-V2 and its effects biological. Finally, we will analyze the evolution of the hormone from its starting point with a common gene with PRL to its actions in the most evolved organisms as a true prohormone.
Part of the book: Growth Hormone