Glioblastoma (GBM) is a fatal human brain tumor of grade IV/4 by WHO classification, with a very poor prognosis. At the molecular level and clinical, GBM has at least two types, primary and secondary. Each has a different tumorigenesis and clinical presentation. In this chapter, some major molecular biomarkers and diagnostic hallmarks of GBM will be reviewed and discussed.
Part of the book: Glioblastoma
Meningiomas are the most common primary brain tumors in adults. They are slow growing, mostly benign tumors affecting primarily older people. Meningiomas comprise a family of neoplasms that are most likely derived from the meningothelial cells of the arachnoid cap cell. Current diagnosis of meningioma has been facilitated by MRI scans, and most patients with meningiomas have good prognosis without affecting the quality of life after successful treatment, like gross total resection (GTR). This chapter will briefly review the molecular basis, clinical diagnosis and grading of meningiomas and the treatment options.
Part of the book: Meningioma