Chapters authored
Helicobacter pylori Infection in Peptic Ulcer Disease among Young People
Peptic Ulcer Disease (PUD) is a common chronic disease of the Gastrointestinal Tract (GIT) worldwide, affecting 87.4 million people with 257,500 mortality turnouts in the year 2015. PUD is a painful open sore that develops in the wall lining of the lower part of the esophagus, the stomach, or the duodenum. PUD has both internal and external causative factors, of which Helicobacter pylori (H. pylori) is a major role player, accounting for 70–95% of its prevalence rate globally. H. pylori infection is acquired generally during the younger ages of life with its various mode of transmission, and with a prevalence rate of 90% in some developing countries, but remains asymptomatic till later years in life. This chapter attempts to provide the overview of H. pylori infection among young people, since they differ from the elderly, in terms of its prevalence rate, its risk factors, its complication rate, its diagnostic tests and managements, and its higher rate of antibiotic resistance.
Part of the book: Peptic Ulcer Disease
The Influence of Helicobacter pylori Infection Treatment on Psoriasis Severity
Helicobacter pylori infection is a condition caused by the gram-negative bacterium H. pylori affecting the mucous lining of the antrum portion of the stomach. At least 50% of the global population fall victim to this condition with Africans proven to have the highest prevalence rate of 70%, followed by South America and Western Asia with 69.4 and 66.6% respectively. In Africa, Nigeria is said to have the highest prevalence rate of H. pylori infection recording 87.7 to 89.7%. H. pylori infection is known to inflict a wide range of gastric complications including Peptic ulcer disease among others, and extra gastric complications such as Neurological diseases, as well as Dermatological diseases. Psoriasis, an autoimmune chronic inflammatory disease of the skin, affecting more than 100 million individuals globally, is one of the dermatological complications of H. pylori infection. It has been noted that H. pylori seem to play a major role in the development of psoriasis. Therefore, this chapter seeks to provide readers with the connection between H. pylori infection and Psoriasis as well as the influence the treatment of H. pylori infection has on Psoriasis severity.
Part of the book: Helicobacter pylori Infection