In cancer treatment, increase in drug resistance and decrease in new chemotherapeutic drugs have become a pressing problem. Hence, searching for novel anticancer agents with less toxicity and high sensitivity is expanding gradually. Many preclinical and clinical studies indicate that natural antioxidants can help combating carcinogenicity and reduce the adverse effects on cancer therapy, when used alone or as adjuvant in chemotherapy. Consequently, marine algae pave the way for exploring more potential antioxidant compounds which have pharmaceutical importance. Algal terpenoids comprise a large group of bioactive compounds that have excellent antioxidative property and can be used as source of antioxidant in cancer therapy. This chapter summarizes the potential role of terpenoids from algal sources in inhibiting cancer cells, blocking cell cycle, hindering angiogenesis and metastasis as well as in inducing apoptosis.
Part of the book: Terpenes and Terpenoids
Climate change is one of the major global concerns jeopardizing human health and wildlife. This event is considered a threat to the marine ecosystem as well. Marine algae are the leading producer in the benthic food chain. Therefore, any change in marine algal communities will disrupt the whole ecosystem. Currently, algal species face significant changes in their abundance and distribution worldwide. Toxic species are frequently invading and causing a phenomenon called the harmful algal bloom, which threatens the seafood industry and public health. This chapter will focus on the significant distribution of algal communities worldwide and the impact of climate change on these marine algal species. Besides, this chapter will shed some light on how these changes affect the marine food chain and ultimately affect human health.
Part of the book: Progress in Microalgae Research