Histamine is a biogenic amine involved in important physiological activities in the organism, but its ingestion through food is associated with the onset of health disorders. Histamine intoxication, previously known as scombroid fish poisoning, is caused by the intake of foods with high levels of histamine. According to official European Union reports, more than 90% of the outbreaks registered in the last years were caused by the consumption of fish and seafood products. Histamine intolerance, on the other hand, arises when histamine degradation is impaired, mainly by a lower diamine oxidase (DAO) activity. Some of the uncertainties classically associated with histamine intoxication may be explained by this enzymatic deficit in a sensitive population. This chapter reviews the adverse effects of histamine from food within a risk analysis framework, focusing specifically on the components of risk assessment and management.
Part of the book: Biogenic Amines
Breastfeeding is the gold standard for infant nutrition in the first six months of life when feeding choices determine growth and development. However, human milk is a complex and highly variable fluid that, in addition to nutrients, contains several bioactive components, including polyamines (putrescine, spermidine, and spermine), and constitutes the first exogenous source of these compounds for infants. Active in various cellular processes, polyamines are involved in the growth and maturation of the gastrointestinal tract and the development of the immune system and therefore play an important role in the first year of life. This chapter reviews the impact of polyamines on infant growth and health, the polyamine content in human milk and how it is influenced by factors related to both the mother-child dyad and breastfeeding itself. In addition, a comparative analysis of human milk and infant formulas in terms of polyamine content and profile is presented.
Part of the book: Infant Nutrition and Feeding