Intestinal transplantation (ITx) has evolved in the past few decades moving from an experimental procedure to a life-changing modality for patients suffering from intestinal failure (IF). It is particularly for those with complications as a consequence of parenteral nutrition and/or who have a high risk of dying due to their underlying disease. In addition to this, intestinal transplantation is also increasingly considered for the treatment of conventionally unresectable abdominal tumors. With advancements in immunosuppressive drugs, induction regimens, standardization of surgical techniques and improved postoperative care, survival is increasing. The ultimate goal for intestinal transplantation would be to become as good and safe as total parenteral nutrition (TPN) and as such, it could become a viable first-line option of intestinal failure.
Part of the book: Organ Donation and Transplantation